SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGen…
☆180Mar 7, 2026Updated 2 weeks ago
Alternatives and similar repositories for SigProfilerExtractor
Users that are interested in SigProfilerExtractor are comparing it to the libraries listed below
Sorting:
- SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations o…☆119Feb 8, 2026Updated last month
- SigProfilerPlotting provides a standard tool for displaying all types of mutational signatures as well as all types of mutational pattern…☆52Feb 8, 2026Updated last month
- Assignment of known mutational signatures to individual samples and individual somatic mutations☆76Feb 19, 2026Updated last month
- SigProfilerSingleSample allows attributing a known set of mutational signatures to an individual sample. The tool identifies the activity…☆23Jan 17, 2025Updated last year
- R wrapper for utilizing the SigProfilerMatrixGenerator framework☆20Jan 29, 2026Updated last month
- SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be use…☆21Feb 10, 2026Updated last month
- An R wrapper for running the SigProfilerPlotting framework☆10Jan 29, 2026Updated last month
- Updated SignatureAnalyzer-GPU with mutational spectra & RNA expression compatibility.☆81Jan 20, 2026Updated 2 months ago
- dN/dS methods to quantify selection in cancer and somatic evolution☆232May 15, 2025Updated 10 months ago
- Tool for analyzing the inter-mutational distances between SNV-SNV and INDEL-INDEL mutations. Tool separates mutations into clustered and …☆14Feb 26, 2026Updated 3 weeks ago
- Mutational signature analysis for low statistics SNV data☆64Aug 7, 2024Updated last year
- The EnsembleVariantCallingPipeline takes files in FASTQ or BAM format and performs SNV and INDEL variant calling from 4 variant callers (…☆14Jul 24, 2025Updated 7 months ago
- DriverPower☆26Jan 18, 2025Updated last year
- Algorithm to implement Fraction and Copy number Estimate from Tumor/normal Sequencing.☆158Feb 12, 2026Updated last month
- deconstructSigs☆144Apr 24, 2023Updated 2 years ago
- Codes and Data for FFPEsig manuscript☆17Jan 17, 2024Updated 2 years ago
- MutSig2CV from Lawrence et al. 2014☆33Aug 18, 2020Updated 5 years ago
- Python function for TMB snake plots☆16Feb 12, 2026Updated last month
- ☆85Apr 17, 2025Updated 11 months ago
- SV clustering☆31Jul 5, 2021Updated 4 years ago
- FInding REliable Variants without ArTifacts☆23Nov 18, 2022Updated 3 years ago
- MuSiCa - Mutational Signatures in Cancer☆23Dec 23, 2023Updated 2 years ago
- 🌲 An easy-to-use and scalable toolkit for genomic alteration signature (a.k.a. mutational signature) analysis and visualization in R htt…☆158Dec 25, 2025Updated 2 months ago
- ☆13Sep 24, 2025Updated 5 months ago
- An R package to time somatic mutations☆67Dec 12, 2020Updated 5 years ago
- SigProfilerTopography allows evaluating the effect of chromatin organization, histone modifications, transcription factor binding, DNA re…☆24Feb 27, 2026Updated 3 weeks ago
- Battenberg R package for subclonal copynumber estimation☆95Feb 20, 2026Updated last month
- ASCAT R package☆199Feb 12, 2026Updated last month
- ABSOLUTE source code that works with allelic copy ratio on both hg19 and hg38☆13Nov 5, 2025Updated 4 months ago
- Support code for NGS copy number algorithms. Takes a file of locations and a [cr|b]am file and generates a count of coverage of each alle…☆44Aug 24, 2022Updated 3 years ago
- R pkg for Hierarchical Dirichlet Process☆83Jul 18, 2023Updated 2 years ago
- HATCHet (Holistic Allele-specific Tumor Copy-number Heterogeneity) is an algorithm that infers allele and clone-specific CNAs and WGDs jo…☆71Mar 13, 2026Updated last week
- An R wrapper for SigProfilerExtractor that allows de novo extraction of mutational signatures from data generated in a matrix format. The…☆15Jan 29, 2026Updated last month
- Summarize, Analyze and Visualize MAF files from TCGA or in-house studies.☆485Feb 25, 2026Updated 3 weeks ago
- Utility functions for FACETS☆39Oct 24, 2025Updated 4 months ago
- An R package for studying mutational signatures and structural variant signatures along clonal evolution in cancer.☆72May 23, 2024Updated last year
- ☆78Jul 12, 2023Updated 2 years ago
- Probabilistic model for inferring clonal population structure from deep NGS sequencing.☆119Aug 19, 2020Updated 5 years ago
- A computational method for inferring the cancer cell fraction of tumour structural variation from whole-genome sequencing data.☆42Aug 21, 2025Updated 6 months ago