wuyangf7 / OPERALinks
This software tool implements the OPERA (omics pleiotropic association) method to test for combinatorial pleiotropic associations of molecular phenotypes (e.g., expression level of a gene and DNA methylation level at CpG sites) with a complex trait of interest using summary-level data from GWAS and molecular QTL studies. OPERA is a Bayesian gene…
☆35Updated last year
Alternatives and similar repositories for OPERA
Users that are interested in OPERA are comparing it to the libraries listed below
Sorting:
- ☆24Updated last month
- harmonization, liftover, and imputation of summary statistics from GWAS☆35Updated 5 years ago
- This is a pipeline for calculating weights for TWAS☆32Updated 3 years ago
- Post-GWAS enrichment, colocalization, TWAS and Mendelian Randomization to integrate molecular QTL and GWAS.☆31Updated last week
- Colocalization analysis of genetic association signals☆53Updated 7 months ago
- R script to make Manhattan-style plot for TWAS☆41Updated 4 years ago
- Tissue-Gene Fine-Mapping☆26Updated 10 months ago
- Automated statistical and functional fine-mapping pipeline with extensive API access to datasets.☆43Updated 3 years ago
- Estimate local SNP heritability and genetic covariance from GWAS summary association statistics.☆42Updated 7 years ago
- Regional association plots☆24Updated last year
- PUMICE: Prediction Using Models Informed by Chromatin conformations and Epigenomics☆12Updated 2 years ago
- corrplot of LDSC genetic correlation results☆56Updated 3 years ago
- Fine-mapping pipeline in R: FINEMAP, CAVIAR, PAINTOR, GCTA-COJO, ABF☆35Updated 7 months ago
- Create Regional Association Plots☆13Updated 5 months ago
- Cross-population fine-mapping☆41Updated last year
- ☆21Updated 6 months ago
- ☆23Updated 3 years ago
- FLAMES: Accurate gene prioritization in GWAS loci☆57Updated last month
- Manhattan++☆28Updated last year
- An R package for creating ggplot2 based miami plots.☆18Updated 11 months ago
- A collection of various utilities for GWAS summary statistics☆32Updated last year
- xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLs☆39Updated last year
- ☆38Updated 5 years ago
- xQTLbiolinks: an R package for integrative analysis with xQTL data☆17Updated 2 weeks ago
- Code supporting analyses in paper on fine-mapping AD loci☆16Updated 4 years ago
- ☆13Updated 3 years ago
- A powerful TWAS framework leveraging summary-level reference data☆32Updated 10 months ago
- ☆57Updated last year
- Methods for converting eQTL summary statistics into TWAS SNP-weights☆13Updated 7 months ago
- ☆24Updated 4 years ago