wuyangf7 / OPERALinks
This software tool implements the OPERA (omics pleiotropic association) method to test for combinatorial pleiotropic associations of molecular phenotypes (e.g., expression level of a gene and DNA methylation level at CpG sites) with a complex trait of interest using summary-level data from GWAS and molecular QTL studies. OPERA is a Bayesian gene…
☆36Updated 10 months ago
Alternatives and similar repositories for OPERA
Users that are interested in OPERA are comparing it to the libraries listed below
Sorting:
- ☆23Updated 2 weeks ago
- Post-GWAS enrichment, colocalization, TWAS and Mendelian Randomization to integrate molecular QTL and GWAS.☆27Updated 2 weeks ago
- This is a pipeline for calculating weights for TWAS☆32Updated 3 years ago
- FLAMES: Accurate gene prioritization in GWAS loci☆41Updated 5 months ago
- harmonization, liftover, and imputation of summary statistics from GWAS☆33Updated 4 years ago
- Automated statistical and functional fine-mapping pipeline with extensive API access to datasets.☆38Updated 2 years ago
- Colocalization analysis of genetic association signals☆52Updated last month
- xQTLbiolinks: an R package for integrative analysis with xQTL data☆17Updated last year
- Software for estimating correlation of trait effect sizes across populations☆47Updated 2 months ago
- Cross-population fine-mapping☆38Updated 8 months ago
- Create Regional Association Plots☆12Updated last year
- Regional association plots☆25Updated last year
- Estimate local SNP heritability and genetic covariance from GWAS summary association statistics.☆41Updated 7 years ago
- A collection of various utilities for GWAS summary statistics☆29Updated last year
- A powerful TWAS framework leveraging summary-level reference data☆31Updated 4 months ago
- ☆57Updated 6 months ago
- Fine-mapping pipeline in R: FINEMAP, CAVIAR, PAINTOR, GCTA-COJO, ABF☆32Updated last month
- ☆23Updated 2 years ago
- R script to make Manhattan-style plot for TWAS☆38Updated 3 years ago
- S-LDSC scripts for use on MR server.☆10Updated 3 years ago
- Assessing enrichment of complex disease or trait associations among QTLs☆15Updated 5 years ago
- Quality control steps for GWAS☆24Updated 2 years ago
- ☆36Updated 4 years ago
- PUMICE: Prediction Using Models Informed by Chromatin conformations and Epigenomics☆12Updated last year
- xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLs☆37Updated 6 months ago
- ☆19Updated last year
- Tissue-Gene Fine-Mapping☆21Updated 4 months ago
- An R package for creating ggplot2 based miami plots.☆17Updated 5 months ago
- Methods for converting eQTL summary statistics into TWAS SNP-weights☆13Updated last month
- Manhattan++☆28Updated last year