mancusolab / twas_sim
Using real genotype data, simulate a complex trait as a function of latent expression, fit eQTL weights in independent data, and perform GWAS/TWAS on complex trait.
☆26Updated last year
Alternatives and similar repositories for twas_sim:
Users that are interested in twas_sim are comparing it to the libraries listed below
- Mediated Expression Score Regression (MESC)☆26Updated 2 years ago
- Code for creating cell-type-specific regulatory element annotation files☆18Updated 10 months ago
- QTL Discovery using Annotations☆24Updated 2 years ago
- ☆13Updated 2 years ago
- An R package for performing MetaSTAAR procedure in whole-genome sequencing studies☆23Updated 5 months ago
- A pure R implementation of locuszoom for plotting genetic data at genomic loci accompanied by gene annotations.☆43Updated 2 months ago
- ☆22Updated 3 years ago
- Colocalization analysis of genetic association signals☆52Updated 5 months ago
- software package for integrative genetic association analysis☆34Updated last year
- MMQTL is a statistical package applying meta-analysis to detect multiple QTL signals integrating signals among conditions, with control f…☆11Updated last month
- Pan-transcriptomic phenotyping☆17Updated last week
- Leveraging functional information to improve GWAS summary statistic imputation☆20Updated 3 years ago
- ☆20Updated 2 years ago
- Software to perform multi-ancestry SNP fine-mapping on molecular data☆21Updated 6 months ago
- Functional genomics and genome-wide association studies☆67Updated 6 years ago
- An R package for creating mirrored Manhattan plots☆18Updated 2 years ago
- Cross-population fine-mapping☆35Updated 4 months ago
- FOCUS: Fine-mapping Of CaUsal gene Sets☆44Updated last year
- Enhanced version of the FastQTL QTL mapper☆64Updated 2 years ago
- A tool to plot significant regions of GWAS☆29Updated 2 years ago
- package for the causal TWAS project☆41Updated this week
- Sequence kernel association test (SKAT)☆49Updated 2 months ago
- Analysis of gene expression and splicing diversity in a subset of samples from the 1000 Genomes Project, including eQTL and sQTL discover…☆36Updated 9 months ago
- ☆20Updated 10 months ago
- A repository containing various scripts useful for performing quality control on data from genome-wide association studies and visualizin…☆20Updated 7 years ago
- ☆46Updated 6 months ago
- ☆21Updated 3 months ago
- Total and allele specific read based cis-QTL, fine-mapping, and prediction☆9Updated 4 years ago
- Manhattan++☆28Updated last year
- Generalized linear Mixed Model Association Tests☆42Updated last year