SigProfilerTopography allows evaluating the effect of chromatin organization, histone modifications, transcription factor binding, DNA replication, and DNA transcription on the activities of different mutational processes. SigProfilerTopography elucidates the unique topographical characteristics of mutational signatures.
☆24May 21, 2026Updated last month
Alternatives and similar repositories for SigProfilerTopography
Users that are interested in SigProfilerTopography are comparing it to the libraries listed below. We may earn a commission when you buy through links labeled 'Ad' on this page.
Sorting:
- Somatic coding and non-coding mutation enrichment analysis for tumor WGS data☆12Jun 16, 2021Updated 5 years ago
- Codes and Data for FFPEsig manuscript☆17Jan 17, 2024Updated 2 years ago
- Code and data from Koche et al. Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma (2020)☆15Nov 5, 2020Updated 5 years ago
- Tool for analyzing the inter-mutational distances between SNV-SNV and INDEL-INDEL mutations. Tool separates mutations into clustered and …☆14Jun 18, 2026Updated last week
- Singularity port of HLA typing based on an input exome BAM file and is currently infers infers alleles for the three major MHC class I (…☆14Jan 15, 2017Updated 9 years ago
- Deploy open-source AI quickly and easily - Special Bonus Offer • AdRunpod Hub is built for open source. One-click deployment and autoscaling endpoints without provisioning your own infrastructure.
- Integrated Genome Modeling (IGM): multi-modal data-driven simulator of genome structures☆12Jun 15, 2023Updated 3 years ago
- Flexible and efficient tests for evidence of positive selection anywhere in the cancer genome.☆27Jul 30, 2022Updated 3 years ago
- NOTE: This package has been renamed to sparrow and will be submitted to Bioconductor 3.14. Please use that package instead. This is kept …☆23Nov 16, 2020Updated 5 years ago
- Computational analyses of WGS, mate-pair, RNA-seq, Hi-C and Capture-C data from highly rearranged balancer chromosomes in Drosophila mela…☆10Sep 25, 2019Updated 6 years ago
- Quantifying copy number signatures from absolute copy number profiles☆27Jul 23, 2025Updated 11 months ago
- ☆12Nov 21, 2023Updated 2 years ago
- Testing a neutral evolution model on cancer sequencing data☆10Feb 17, 2021Updated 5 years ago
- Clonal structure identification through penalizing pairwise differences☆11May 14, 2026Updated last month
- SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations o…☆122May 26, 2026Updated last month
- Deploy open-source AI quickly and easily - Special Bonus Offer • AdRunpod Hub is built for open source. One-click deployment and autoscaling endpoints without provisioning your own infrastructure.
- Marker Selection by matching manifolds and elastic net☆23Oct 22, 2024Updated last year
- ☆86Apr 17, 2025Updated last year
- Mutational signature analysis for low statistics SNV data☆66Aug 7, 2024Updated last year
- TF analysis from epigenetic and Hi-C data☆19Apr 1, 2025Updated last year
- Accucopy is a computational method that infers Allele-Specific Copy Number alterations from low-coverage low-purity tumor sequencing data…☆17Mar 6, 2024Updated 2 years ago
- ☆12Feb 19, 2021Updated 5 years ago
- Code accompanying Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes☆44Apr 16, 2021Updated 5 years ago
- Code accompanying The Evolutionary history of 2,658 cancers☆48Apr 16, 2021Updated 5 years ago
- ☆12Jan 8, 2026Updated 5 months ago
- Managed Database hosting by DigitalOcean • AdPostgreSQL, MySQL, MongoDB, Kafka, Valkey, and OpenSearch available. Automatically scale up storage and focus on building your apps.
- Code repo for all analysis done for the 'Pan-cancer whole genome comparison of primary and metastatic solid tumors' study.☆17May 11, 2023Updated 3 years ago
- Integrating long read sequencing enhances short read-based locus-specific transposable element quantification☆11May 12, 2025Updated last year
- Irons out wrinkles in noisy coverage data using robust PCA☆15May 14, 2025Updated last year
- SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the n…☆186Jun 18, 2026Updated last week
- R package for extracting and visualizing mutational patterns in base substitution catalogues☆107Nov 22, 2022Updated 3 years ago
- CALDER (Cancer Analysis of Longitudinal Data through Evolutionary Reconstruction) reconstructs evolutionary trees from longitudinal bulk …☆15Nov 28, 2023Updated 2 years ago
- Code associated with the manuscript "A complete reference genome improves analysis of human genetic variation".☆17Jan 17, 2023Updated 3 years ago
- Mutational Signature Comprehensive Analysis Toolkit☆16Apr 11, 2026Updated 2 months ago
- ☆12Sep 22, 2025Updated 9 months ago
- 1-Click AI Models by DigitalOcean Gradient • AdDeploy popular AI models on DigitalOcean Gradient GPU virtual machines with just a single click. Zero configuration with optimized deployments.
- ☆13Sep 18, 2017Updated 8 years ago
- Prostate Cancer Alteration Signature Analysis https://xsliulab.github.io/PC_CNA_signature/☆13May 17, 2021Updated 5 years ago
- Detects human contamination in bam files☆16Sep 10, 2020Updated 5 years ago
- Interactive visualisation of CellphoneDB results☆13Jan 15, 2025Updated last year
- ☆18Jan 30, 2023Updated 3 years ago
- A python wrapper around SURVIVOR☆20Feb 15, 2024Updated 2 years ago
- ☆14Oct 9, 2025Updated 8 months ago