HeliXonProtein / proximal-explorationView external linksLinks
PyTorch implementation for our paper "Proximal Exploration for Model-guided Protein Sequence Design"
☆37Aug 7, 2023Updated 2 years ago
Alternatives and similar repositories for proximal-exploration
Users that are interested in proximal-exploration are comparing it to the libraries listed below
Sorting:
- Bayesian Optimization with Pretrained Protein Sequence Models☆56Jul 27, 2024Updated last year
- ☆17Jun 27, 2025Updated 7 months ago
- Fitness landscape exploration sandbox for biological sequence design.☆170Feb 16, 2023Updated 2 years ago
- Official repository for "Plug & Play Directed Evolution for Proteins with Gradient-Based Discrete MCMC"☆12Jul 18, 2023Updated 2 years ago
- ☆33Oct 31, 2022Updated 3 years ago
- ☆76Oct 27, 2021Updated 4 years ago
- This repository is the official implementation of Bidirectional Learning for Offline Infinite-width Model-based Optimization (NeurIPS 202…☆14Jan 19, 2023Updated 3 years ago
- Code fo ICLR2025 paper "A Simple yet Effective DDG Predictor is An Unsupervised Antibody Optimizer and Explainer"☆21Jul 18, 2025Updated 6 months ago
- Repository for code and models for the paper "Extrapolative Controlled Sequence Generation via Iterative Refinement"☆16Mar 5, 2024Updated last year
- Neurally-derived Potts models for protein design, inspired by dTERMen☆14Aug 23, 2022Updated 3 years ago
- ☆34May 1, 2025Updated 9 months ago
- Implementation of the DDPM + IPA (invariant point attention) for protein generation, as outlined in the paper "Protein Structure and Sequ…☆89Jul 25, 2022Updated 3 years ago
- ☆16Aug 14, 2019Updated 6 years ago
- ✌🏻 Antigen-Specific Antibody Design and Optimization with Diffusion-Based Generative Models for Protein Structures (NeurIPS 2022)☆353Jun 29, 2023Updated 2 years ago
- Tool for modelling the CDRs of antibodies☆50Jan 19, 2023Updated 3 years ago
- Official repository for the paper "Tranception: Protein Fitness Prediction with Autoregressive Transformers and Inference-time Retrieval"☆163Aug 24, 2023Updated 2 years ago
- Repository for Fast Non-autoregressive Inverse Folding with Discrete Diffusion☆18Feb 8, 2024Updated 2 years ago
- Code to reproduce experiments in "Accelerating Bayesian Optimization for Protein Design with Denoising Autoencoders" (Stanton et al 2022)☆74May 19, 2024Updated last year
- Meta learning addresses noisy and under-labeled data in machine learning-guided antibody engineering (https://doi.org/10.1016/j.cels.2023…☆20Aug 8, 2024Updated last year
- Computational predictor of protein intrinsic disorder and its functions☆10Dec 4, 2023Updated 2 years ago
- This is the official code repository for the paper FLOP: Tasks for Fitness Landscapes Of Protein wildtypes by Groth et al.☆22Jun 26, 2023Updated 2 years ago
- AbLang: A language model for antibodies☆157Sep 22, 2023Updated 2 years ago
- ☆130Sep 5, 2022Updated 3 years ago
- Protein generative model conditioned on Gene Ontology terms☆35Jul 17, 2022Updated 3 years ago
- Unconstrained lattice antibody-antigen bindings generator☆111Nov 16, 2025Updated 2 months ago
- ☆23Jun 10, 2025Updated 8 months ago
- This repository implements Gibbs sampling with Graph-based Smoothing☆41May 29, 2024Updated last year
- Implementation of Protein Invariant Point Packer (PIPPack)☆35May 28, 2024Updated last year
- Generative Language Modeling for Antibody Design☆180Oct 5, 2024Updated last year
- ☆14Jul 14, 2023Updated 2 years ago
- Code for the paper "Learning to engineer protein flexibility".☆22Jan 21, 2026Updated 3 weeks ago
- A library of discrete objectives☆24Oct 5, 2025Updated 4 months ago
- ☆212Sep 24, 2024Updated last year
- A collection of tools that generate and analyse side-chain rotamer libraries☆10Updated this week
- Official open-source of Antibody Design Using a Score-based Diffusion Model Guided by Evolutionary, Physical, and Geometric Constraints☆47Jun 30, 2025Updated 7 months ago
- Protein scoring and sampling of 'Combinatorial Variant Effects from Structure' (CoVES)☆11Jan 5, 2024Updated 2 years ago
- Code for the ICML 2019 paper 'Conditioning by adaptive sampling for robust design'☆37Jun 4, 2021Updated 4 years ago
- ☆136Aug 8, 2024Updated last year
- [NeurIPS 2025 spotlight] Efficient factorized variant of the IPA module.☆45Nov 14, 2025Updated 3 months ago