Alternatives and similar repositories for ODesign

Users that are interested in ODesign are comparing it to the libraries listed below

• Kuhlman-Lab / ThermoMPNN
  GNN trained to predict changes in thermodynamic stability for protein point mutants
  ☆219Updated 5 months ago
• yehlincho / BoltzDesign1
  ☆234Updated 5 months ago
• LPDI-EPFL / masif-neosurf
  MaSIF-neosurf: surface-based protein design for ternary complexes.
  ☆163Updated last month
• ikalvet / heme_binder_diffusion
  ☆146Updated 6 months ago
• YuzheWangPKU / DiffPepBuilder
  Official repository for DiffPepBuilder and DiffPepDock tools
  ☆113Updated 2 months ago
• bcov77 / silent_tools
  A bunch of shell utilities for dealing the silent files
  ☆73Updated 2 weeks ago
• levinthal / Pallatom
  ☆134Updated 7 months ago
• richardshuai / fampnn
  Sidechain conditioning and modeling for full-atom protein sequence design
  ☆132Updated 2 months ago
• baker-laboratory / PLACER
  PLACER is graph neural network for local prediction of protein-ligand conformational ensembles.
  ☆222Updated 2 months ago
• bytedance / Protenix-Dock
  An accurate and trainable end-to-end protein-ligand docking framework
  ☆118Updated 9 months ago
• DunbrackLab / IPSAE
  Scoring function for interprotein interactions in AlphaFold2 and AlphaFold3
  ☆188Updated 2 weeks ago
• ELELAB / RosettaDDGPrediction
  ☆84Updated last month
• zhanghaicang / carbonmatrix_public
  ☆119Updated 2 weeks ago
• Mingchenchen / AF3Score
  A Score-Only Adaptation of AlphaFold3 for Biomolecular Structure Evaluation
  ☆81Updated 5 months ago
• Wublab / Pythia
  Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutations
  ☆88Updated last month
• programmablebio / pepmlm
  Target Sequence-Conditioned Generation of Peptide Binders via Masked Language Modeling
  ☆109Updated 2 months ago
• SantiagoMille / germinal
  Codebase for Germinal, a broadly enabling generative pipeline for efficient generation of epitope-targeted de novo antibodies.
  ☆180Updated last month
• ai4protein / Pro-Prime
  ☆77Updated 4 months ago
• HWaymentSteele / AF_Cluster
  Predict multiple protein conformations using sequence clustering and AlphaFold2.
  ☆171Updated 3 months ago
• A-Alpha-Bio / alphabind
  AlphaBind code + model accompanying pre-print
  ☆87Updated 5 months ago
• Graylab / FLAb
  Fitness landscapes for antibodies
  ☆132Updated 3 weeks ago
• LBM-EPFL / PeSTo
  Geometric deep learning method to predict protein binding interfaces from a protein structure.
  ☆153Updated 2 years ago
• ai4protein / VenusREM
  🧬 Augmenting zero-shot mutant prediction by retrieval-based logits fusion. (ISMB/ECCB 2025)
  ☆122Updated 5 months ago
• WillHua127 / EnzymeFlow
  Official repository of EnzymeFlow
  ☆97Updated last year
• drhicks / Kejia_peptide_binders
  code for IDR binding paper 2025
  ☆65Updated 11 months ago
• colbyford / PyMOLfold
  Plugin for folding sequences directly in PyMOL
  ☆115Updated 5 months ago
• hefeda / design_tools
  A compilation of deep learning methods for protein design
  ☆97Updated 3 years ago
• WillHua127 / GENzyme
  Official repository of GENzyme
  ☆60Updated last year
• jproney / AF2Rank
  ☆114Updated 3 years ago
• maranasgroup / CatPred
  Machine Learning models for in vitro enzyme kinetic parameter prediction
  ☆69Updated 9 months ago