lehner-lab / doubledeepms
Source code for fitting thermodynamic models (MoCHI), downstream analyses and to reproduce all figures in the following publication: Mapping the energetic and allosteric landscapes of protein binding domains (Faure AJ, Domingo J & Schmiedel JM et al., 2022)
☆19Updated last year
Alternatives and similar repositories for doubledeepms:
Users that are interested in doubledeepms are comparing it to the libraries listed below
- Neural networks to fit interpretable models and quantify energies, energetic couplings, epistasis, and allostery from deep mutational sca…☆46Updated 3 weeks ago
- ☆49Updated last month
- Machine learning models for antibody sequences in PyTorch☆39Updated 3 years ago
- Machine learning prediction of enzyme optimum pH☆33Updated last week
- Code and data to reproduce analyses in Biswas et al. (2020) "Low-N protein engineering with data-efficient deep learning".☆58Updated 4 years ago
- An antibody-specific language model focusing on NGL prediction☆27Updated 8 months ago
- ☆23Updated 2 years ago
- ☆21Updated 4 months ago
- Fragment binding prediction with ColabFold☆33Updated last month
- ☆40Updated last month
- DE-STRESS is a model evaluation pipeline that aims to make protein design more reliable and accessible.☆24Updated 2 months ago
- Metrics for our protein design competitions.☆27Updated 6 months ago
- Repository for Protein-Vec, a protein embedding mixture of experts model☆37Updated last year
- Deciphering protein evolution and fitness landscapes with latent space models☆32Updated 3 years ago
- Active Learning-Assisted Directed Evolution for Protein Engineering☆50Updated 5 months ago
- A tool for accurate prediction of a protein's secondary structure from only it's amino acid sequence☆54Updated last month
- Python tool for the discovery of similar 3D structural motifs across protein structures.☆27Updated last year
- ☆19Updated 3 weeks ago
- Kuhlman Lab Installation of AlphaFold3☆25Updated last month
- An unofficial re-implementation of AntiBERTy, an antibody-specific protein language model, in PyTorch.☆24Updated last year
- ☆27Updated 11 months ago
- A domain parser for Alphafold models☆35Updated last year
- Fast and accurate protein domain segmentation using Invariant Point Attention☆38Updated 5 months ago
- Learning the language of protein-protein interactions☆72Updated 2 weeks ago
- KA-Search: Rapid and exhaustive sequence identity search of known antibodies☆22Updated 9 months ago
- Scoring function for interprotein interactions in AlphaFold2 and AlphaFold3☆49Updated 3 weeks ago
- ☆66Updated last month
- ☆38Updated 3 months ago
- Results and data from the pilot round of the Protein Engineering Tournament☆29Updated last month
- ☆37Updated last year