gitter-lab / metl
Mutational Effect Transfer Learning (METL) framework for pretraining and finetuning biophysics-informed protein language models
☆34Updated this week
Alternatives and similar repositories for metl:
Users that are interested in metl are comparing it to the libraries listed below
- ☆64Updated 3 weeks ago
- ☆43Updated 6 months ago
- Novel estimator for the change in stability upon point mutation in monomeric and multimeric proteins.☆45Updated 4 months ago
- Generating and scoring novel enzyme sequences with a variety of models and metrics☆70Updated 2 months ago
- Deep learning framework for protein sequence design from a backbone scaffold that can leverage the molecular context including non-protei…☆39Updated 4 months ago
- ☆34Updated 6 months ago
- Efficient manipulation of protein structures in Python☆53Updated 5 months ago
- ☆36Updated last year
- Active Learning-Assisted Directed Evolution for Protein Engineering☆46Updated 4 months ago
- ☆77Updated last month
- Code for the paper "Learning to engineer protein flexibility".☆16Updated 2 weeks ago
- Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutations☆56Updated 2 months ago
- Structure prediction of alternative protein conformations☆75Updated last month
- Controlling the usage of hydrophobic residues on AfDesign for binder peptide design with AlphaFold hallucination protocol☆31Updated last year
- Metrics for our protein design competitions.☆26Updated 5 months ago
- Official implementation of Generative Diffusion Models for Antibody Design, Docking, and Optimization.☆57Updated last year
- ☆27Updated 4 months ago
- Extension of ThermoMPNN for double mutant predictions☆32Updated 3 weeks ago
- ☆26Updated 2 months ago
- An antibody-specific language model focusing on NGL prediction☆26Updated 7 months ago
- ☆18Updated 5 months ago
- ☆37Updated 3 months ago
- Target Sequence-Conditioned Generation of Peptide Binders via Masked Language Modeling☆51Updated 8 months ago
- NuFold: End-to-End Approach for RNA Tertiary Structure Prediction with Flexible Nucleobase Center Representation☆32Updated last week
- dMaSIF implementation for google colab☆32Updated 2 years ago
- The official implementation of DiffAbXL benchmarked in the paper "Exploring Log-Likelihood Scores for Ranking Antibody Sequence Designs",…☆68Updated 5 months ago
- Guiding diffusion models for antibody sequence and structure co-design with developability properties.☆32Updated 5 months ago
- Fast deep learning methods for large-scale protein-protein interaction screening☆36Updated 6 months ago
- Exploring the conformational ensembles of protein-protein complexes with transformer-based generative neural networks☆28Updated 10 months ago
- Code for humanization of antibody and nanobody☆39Updated 4 months ago