The Loss-of-Function ToolKit (LoFTK) allows efficient and automated prediction of LoF variants from both genotyped and sequenced genomes, identifying genes that are inactive in one or two copies, and providing summary statistics for downstream analyses.
β10Jul 30, 2025Updated last year
Alternatives and similar repositories for LoFTK
Users that are interested in LoFTK are comparing it to the libraries listed below. We may earn a commission when you buy through links labeled 'Ad' on this page.
Sorting:
- Network representation learning on drug-target-side effects-indication graphs for side effect predictionβ13Feb 4, 2020Updated 6 years ago
- π© A Monte Carlo simulation of Monopoly board gameβ17Jan 7, 2020Updated 6 years ago
- Polynomial Mendelian randomization for the inference of non-linear causal effectsβ14Apr 20, 2023Updated 3 years ago
- π Generation and Applications of Knowledge Graphs in Systems and Networks Biologyβ33Dec 16, 2019Updated 6 years ago
- A collection of scripts to run GWAS, regional, gene-oriented, or per-variant analyses.β18Oct 2, 2026Updated last week
- End-to-end encrypted email - Proton Mail β’ AdSpecial offer: 40% Off Yearly / 80% Off First Month. All Proton services are open source and independently audited for security.
- Method for Identifying Novel Transcripts and Isoforms using Equivalence classes, in cancer and rare disease.β38Jul 1, 2024Updated 2 years ago
- Boiler: a software tool for highly efficient, lossy compression of RNA-seq alignmentsβ13Jul 14, 2016Updated 10 years ago
- Clinical Variant Annotation Pipelineβ10Apr 21, 2020Updated 6 years ago
- Plot allele frequencies in VCF filesβ11Apr 13, 2026Updated 6 months ago
- Nextflow implementation of the GATK HaplotypeCaller pipelineβ13Dec 27, 2025Updated 9 months ago
- Analyses conducting GWAS across the UKBB diverse superpopulationsβ67Oct 22, 2025Updated 11 months ago
- β13Oct 13, 2021Updated 5 years ago
- Tools for processing Nightingale NMR biomarker data in UK Biobankβ66Jul 7, 2026Updated 3 months ago
- Predict the functional consequences of both coding and non-coding single nucleotide variants (SNVs)β19Mar 18, 2021Updated 5 years ago
- Virtual machines for every use case on DigitalOcean β’ AdGet dependable uptime with 99.99% SLA, simple security tools, and predictable monthly pricing with DigitalOcean's virtual machines, called Droplets.
- Automated ACMG/AMP classification for human variants associated with congenital hearing lossβ11May 14, 2025Updated last year
- Polyidus provides a framework to catch chimeric DNA sequences with a tale of pythonβ10Jul 14, 2023Updated 3 years ago
- The Exome Coverage and Identification Report displays the coverage of every target region in your capture design. It also displays regioβ¦β14Apr 22, 2015Updated 11 years ago
- Cancer Predisposition Sequencing Reporter (CPSR)β66Oct 5, 2026Updated last week
- Expedite large-scale identification of CNVs within predefined genomic regions. Online app available for those with GP2 Tier 2 Access.β14Mar 16, 2026Updated 6 months ago
- CNV calling algorithm for detection of homozygous and hemizygous deletions from whole exome sequencing dataβ12Nov 9, 2025Updated 11 months ago
- Ribosome profiling analysis framework as described in de Klerk E., Fokkema I.F.A.C et al (2015). Alignment, triplet periodicity analysis,β¦β12May 16, 2023Updated 3 years ago
- add true-negative SVs from a population callset to a truth-set.β14Jun 17, 2022Updated 4 years ago
- Biological Network Integration using Convolutionsβ66Jan 17, 2024Updated 2 years ago
- Wordpress hosting with auto-scaling - Free Trial Offer β’ AdFully Managed hosting for WordPress and WooCommerce businesses that need reliable, auto-scalable performance. Cloudways SafeUpdates now available.
- β12May 7, 2017Updated 9 years ago
- Initial data release for drug-target interactions of the cancer targetome.β16Jul 8, 2021Updated 5 years ago
- Pipeline to filter whole exome vcf files and generate a report document for clinical diagnostics.β14Nov 11, 2019Updated 6 years ago
- Tutorials on data science/machine learning using Python with a life-science perspective. When I started learning programming and machine β¦β12Jun 18, 2022Updated 4 years ago
- Variant catalogue pipelineβ26Jan 30, 2026Updated 8 months ago
- Browser for ExAC consortium dataβ11Oct 23, 2017Updated 8 years ago
- Big Browser watching your genomeβ11Apr 10, 2016Updated 10 years ago
- Extensible quality control dashboard built around FASTQ assessment.β15May 17, 2019Updated 7 years ago
- β20Nov 30, 2023Updated 2 years ago
- Deploy to Railway using AI coding agents - Free Credits Offer β’ AdUse Claude Code, Codex, OpenCode, and more. Autonomous software development now has the infrastructure to match with Railway.
- A mini course on biological data analysisβ10Jan 16, 2025Updated last year
- Detection of copy number changes in Germline/Trio/Somatic contexts in NGS dataβ95Jun 29, 2026Updated 3 months ago
- A library to assist with a variety of -omic analyses. Included are tools for proteomics, transcriptomics, and genomics.β16Aug 3, 2023Updated 3 years ago
- Library for indexing VCF files for random access searches by rsIDβ17Mar 2, 2026Updated 7 months ago
- Rare Disease variant reanalysis toolβ86Updated this week
- A Boolean Algebra for Genetic Variantsβ14Sep 4, 2026Updated last month
- β202Jun 20, 2023Updated 3 years ago