The Loss-of-Function ToolKit (LoFTK) allows efficient and automated prediction of LoF variants from both genotyped and sequenced genomes, identifying genes that are inactive in one or two copies, and providing summary statistics for downstream analyses.
β10Jul 30, 2025Updated last year
Alternatives and similar repositories for LoFTK
Users that are interested in LoFTK are comparing it to the libraries listed below. We may earn a commission when you buy through links labeled 'Ad' on this page.
Sorting:
- Network representation learning on drug-target-side effects-indication graphs for side effect predictionβ13Feb 4, 2020Updated 6 years ago
- π© A Monte Carlo simulation of Monopoly board gameβ17Jan 7, 2020Updated 6 years ago
- Polynomial Mendelian randomization for the inference of non-linear causal effectsβ14Apr 20, 2023Updated 3 years ago
- π Generation and Applications of Knowledge Graphs in Systems and Networks Biologyβ33Dec 16, 2019Updated 6 years ago
- A collection of scripts to run GWAS, regional, gene-oriented, or per-variant analyses.β18Jan 21, 2026Updated 6 months ago
- Managed Database hosting by DigitalOcean β’ AdPostgreSQL, MySQL, MongoDB, Kafka, Valkey, and OpenSearch available. Automatically scale up storage and focus on building your apps.
- Method for Identifying Novel Transcripts and Isoforms using Equivalence classes, in cancer and rare disease.β38Jul 1, 2024Updated 2 years ago
- Boiler: a software tool for highly efficient, lossy compression of RNA-seq alignmentsβ13Jul 14, 2016Updated 10 years ago
- Clinical Variant Annotation Pipelineβ10Apr 21, 2020Updated 6 years ago
- Plot allele frequencies in VCF filesβ11Apr 13, 2026Updated 4 months ago
- Nextflow implementation of the GATK HaplotypeCaller pipelineβ13Dec 27, 2025Updated 7 months ago
- Analyses conducting GWAS across the UKBB diverse superpopulationsβ67Oct 22, 2025Updated 9 months ago
- β12Oct 13, 2021Updated 4 years ago
- Tools for processing Nightingale NMR biomarker data in UK Biobankβ66Jul 7, 2026Updated last month
- Predict the functional consequences of both coding and non-coding single nucleotide variants (SNVs)β19Mar 18, 2021Updated 5 years ago
- Bare Metal GPUs on DigitalOcean Gradient AI β’ AdPurpose-built for serious AI teams training foundational models, running large-scale inference, and pushing the boundaries of what's possible.
- Automated ACMG/AMP classification for human variants associated with congenital hearing lossβ11May 14, 2025Updated last year
- Polyidus provides a framework to catch chimeric DNA sequences with a tale of pythonβ10Jul 14, 2023Updated 3 years ago
- The Exome Coverage and Identification Report displays the coverage of every target region in your capture design. It also displays regioβ¦β14Apr 22, 2015Updated 11 years ago
- Cancer Predisposition Sequencing Reporter (CPSR)β65Updated this week
- Expedite large-scale identification of CNVs within predefined genomic regions. Online app available for those with GP2 Tier 2 Access.β14Mar 16, 2026Updated 4 months ago
- CNV calling algorithm for detection of homozygous and hemizygous deletions from whole exome sequencing dataβ12Nov 9, 2025Updated 9 months ago
- Ribosome profiling analysis framework as described in de Klerk E., Fokkema I.F.A.C et al (2015). Alignment, triplet periodicity analysis,β¦β12May 16, 2023Updated 3 years ago
- add true-negative SVs from a population callset to a truth-set.β14Jun 17, 2022Updated 4 years ago
- Biological Network Integration using Convolutionsβ66Jan 17, 2024Updated 2 years ago
- 1-Click AI Models by DigitalOcean Gradient β’ AdDeploy popular AI models on DigitalOcean Gradient GPU virtual machines with just a single click. Zero configuration with optimized deployments.
- β12May 7, 2017Updated 9 years ago
- Initial data release for drug-target interactions of the cancer targetome.β16Jul 8, 2021Updated 5 years ago
- Tutorials on data science/machine learning using Python with a life-science perspective. When I started learning programming and machine β¦β12Jun 18, 2022Updated 4 years ago
- Pipeline to filter whole exome vcf files and generate a report document for clinical diagnostics.β14Nov 11, 2019Updated 6 years ago
- Variant catalogue pipelineβ26Jan 30, 2026Updated 6 months ago
- Browser for ExAC consortium dataβ11Oct 23, 2017Updated 8 years ago
- Big Browser watching your genomeβ11Apr 10, 2016Updated 10 years ago
- Extensible quality control dashboard built around FASTQ assessment.β15May 17, 2019Updated 7 years ago
- β20Nov 30, 2023Updated 2 years ago
- GPU virtual machines on DigitalOcean Gradient AI β’ AdGet to production fast with high-performance AMD and NVIDIA GPUs you can spin up in seconds. The definition of operational simplicity.
- A mini course on biological data analysisβ10Jan 16, 2025Updated last year
- Detection of copy number changes in Germline/Trio/Somatic contexts in NGS dataβ96Jun 29, 2026Updated last month
- A library to assist with a variety of -omic analyses. Included are tools for proteomics, transcriptomics, and genomics.β16Aug 3, 2023Updated 3 years ago
- Library for indexing VCF files for random access searches by rsIDβ17Mar 2, 2026Updated 5 months ago
- Rare Disease variant reanalysis toolβ73Updated this week
- A Boolean Algebra for Genetic Variantsβ14Jul 6, 2026Updated last month
- β200Jun 20, 2023Updated 3 years ago