AlexandrovLab / SigProfilerSimulatorLinks
SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be used to simulate signatures of single point mutations, double point mutations, and insertion/deletions. Further, the tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
☆19Updated last week
Alternatives and similar repositories for SigProfilerSimulator
Users that are interested in SigProfilerSimulator are comparing it to the libraries listed below
Sorting:
- Main repository for Drews et al. (Nature, 2022)☆41Updated last year
- SV clustering☆28Updated 3 years ago
- Dirichlet Process based methods for subclonal reconstruction of tumours☆29Updated 2 months ago
- Model-based subclonal deconvolution from bulk sequencing.☆33Updated 5 months ago
- DriverPower☆26Updated 4 months ago
- Codes and Data for FFPEsig manuscript☆17Updated last year
- ☆13Updated 7 years ago
- CNApp represents the first web tool to perform a comprehensive and integrative analysis of copy number alterations (CNAs) in a user-frien…☆20Updated 5 years ago
- MutSig2CV from Lawrence et al. 2014☆31Updated 4 years ago
- An R package for predicting HR deficiency from mutation contexts☆28Updated 3 months ago
- Comprehensive genome-wide visualization of absolute copy number and copy neutral variations☆29Updated 6 years ago
- SigProfilerPlotting provides a standard tool for displaying all types of mutational signatures as well as all types of mutational pattern…☆48Updated 2 months ago
- Chimeric transcript discovery☆9Updated 7 years ago
- An R package to time somatic mutations☆61Updated 4 years ago
- Rocking R at UMCCR☆9Updated 4 years ago
- SQUID detects both fusion-gene and non-fusion-gene structural variations from RNA-seq data☆42Updated 3 years ago
- Irons out wrinkles in noisy coverage data using robust PCA☆14Updated 3 weeks ago
- An R package for studying mutational signatures and structural variant signatures along clonal evolution in cancer.☆71Updated last year
- Fork of https://bitbucket.org/mcgranahanlab/lohhla☆17Updated 5 years ago
- Combined mutation recurrence and functional impact to identify coding and non-coding cancer drivers☆15Updated 6 years ago
- A computational method for inferring the cancer cell fraction of tumour structural variation from whole-genome sequencing data.☆41Updated last month
- ☆14Updated 3 years ago
- Support code for NGS copy number algorithms. Takes a file of locations and a [cr|b]am file and generates a count of coverage of each alle…☆45Updated 2 years ago
- A neoantigen calling pipeline begins from variants record file (MAF) (Not maintain now)☆29Updated 5 years ago
- Fork from https://bitbucket.org/mcgranahanlab/lohhla/src, modified for MSKCC needs☆31Updated last year
- A tool kit for dissecting cancer evolution from multi-region derived tumor biopsies via somatic mutations☆36Updated 3 years ago
- A fast and robust pre-processing pipeline for bulk or single-cell whole-genome bisulfite sequencing (WGBS) data.☆35Updated 3 years ago
- Utility functions for FACETS☆35Updated last year
- ☆17Updated 3 years ago
- DeTiN is designed to measure tumor-in-normal contamination and improve somatic variant detection sensitivity when using a contaminated ma…☆50Updated 3 years ago