Wublab / Pythia
Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutations
☆56Updated 2 months ago
Alternatives and similar repositories for Pythia:
Users that are interested in Pythia are comparing it to the libraries listed below
- Deep learning framework for protein sequence design from a backbone scaffold that can leverage the molecular context including non-protei…☆39Updated 5 months ago
- ☆76Updated last month
- ☆43Updated 7 months ago
- ☆66Updated last month
- Small_molecule_binder_design_use_pseudocycles☆18Updated 5 months ago
- HyperMPNN ‒ A general strategy to design thermostable proteins learned from hyperthermophiles☆54Updated 2 months ago
- Exploring the conformational ensembles of protein-protein complexes with transformer-based generative neural networks☆29Updated 10 months ago
- Efficient manipulation of protein structures in Python☆53Updated 6 months ago
- Official open-source of CarbonNovo: Joint Design of Protein Structure and Sequence Using a Unified Energy-based Model☆21Updated 5 months ago
- ☆81Updated 7 months ago
- Active Learning-Assisted Directed Evolution for Protein Engineering☆50Updated 5 months ago
- ☆49Updated last month
- ☆38Updated 3 months ago
- ML-optimized library design with improved fitness and diversity for protein engineering☆32Updated 9 months ago
- Machine Learning models for in vitro enzyme kinetic parameter prediction☆43Updated 3 weeks ago
- Scripts to run AlphaFold3, Boltz-1 and Chai-1 with MMseqs2 MSAs and custom templates.☆70Updated this week
- Novel estimator for the change in stability upon point mutation in monomeric and multimeric proteins.☆46Updated 4 months ago
- ☆65Updated 2 months ago
- Code for humanization of antibody and nanobody☆39Updated 5 months ago
- Data sharing for High-throughput Prediction of Changes in Protein Conformational Distributions with Subsampled AlphaFold2☆39Updated 11 months ago
- 🧬 Augmenting zero-shot mutant prediction by retrieval-based logits fusion. (ISMB/ECCB 2025)☆57Updated 2 weeks ago
- A bundle of deep-learning packages for biomolecular structure prediction and design contributed to the Rosetta Commons☆35Updated 2 years ago
- Official implementation of Generative Diffusion Models for Antibody Design, Docking, and Optimization.☆58Updated last year
- Official repository of GENzyme☆49Updated 5 months ago
- Making Protein folding accessible to all!☆22Updated last year
- ☆23Updated last month
- Computer aided proximal decaging as a universal strategy for temporal protein activation☆23Updated 5 years ago
- Modelling of Large Protein Complexes☆37Updated last year
- ☆18Updated 6 months ago
- Scoring function for interprotein interactions in AlphaFold2 and AlphaFold3☆49Updated 3 weeks ago